Potency of Solid Lipid Nanoparticle (SLN)-Modified Luteolin-based Polyethylene Glycol (PEG) on Allium fistulosum as Innovation Therapy of Malaria Falciparum
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چکیده
منابع مشابه
Immunogenicity of Polyethylene Glycol (PEG)
Covalent attachment of polyethylene glycol (PEG) to active proteins (PEGylation technology) successfully generated several FDA-approved compounds, including four blockbusters, which are considered non immunogenic. However, PEG antibodies and intolerance to the infusion were reported in some patients with gout treated with pegloticase, a PEG-uricase recently approved by the FDA (Food and Drug Ad...
متن کاملEffect of freeze-thawing and polyethylene glycol (PEG) lipid on fusion and fission of phospholipid vesicles.
The effect of freeze-thawing on the size of egg yolk phosphatidylcholine (EggPC) vesicles in the presence of 0-40 mol% distearoylphosphatidylethanolamine-polyethylene glycol 2000 (DSPE-PEG) was studied. Mean diameters of the vesicles fell into a range of 80-150 nm after 10 times freeze-thawing in spite of their original size. In the process of freeze-thawing, two opponent events, one is fission...
متن کاملIn vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection
BACKGROUND DOTAP/cholesterol-based lipoplexes are successfully used for delivery of plasmid DNA in vivo especially to the lungs, although low systemic stability and circulation have been reported. To achieve the aim of discovering the best method for systemic delivery of DNA to disseminated tumors we evaluated the potential of formulating DOTAP/cholesterol lipoplexes with a polyethylene glycol ...
متن کاملPreparation, properties and preclinical pharmacokinetics of low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle
Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...
متن کاملRemoval of Mercury (II) from Wastewater by Magnetic Solid Phase Extraction with Polyethylene Glycol (PEG)-Coated Fe3O4 Nanoparticles
The presented study investigates application of polyethylene glycol (PEG)-coated Fe3O4 nanoparticles as an magnetic nanoadsorbent for magnetic solid-phase extraction (SPE) and the selective removal of toxic heavy metals such as mercury (II) from aqueous solutions and their determination using graphite furnace atomic absorption spectrometry (GF-AAS)...
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ژورنال
عنوان ژورنال: KnE Life Sciences
سال: 2021
ISSN: 2413-0877
DOI: 10.18502/kls.v0i0.8898